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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay23302-5 | 5 mg | - |
6 - 10 business days* |
242.00€
|
|||
Cay23302-25 | 25 mg | - |
6 - 10 business days* |
1,135.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Chlortetracycline is a broad-spectrum antibiotic originally isolated from S. aureofaciens. It... more
Product information "Chlortetracycline"
Chlortetracycline is a broad-spectrum antibiotic originally isolated from S. aureofaciens. It inhibits growth of both Gram-positive and Gram-negative bacteria at a range of 0.1-100 µg/ml against A. aerogenes, D. pneumoniae, E. coli, K. pneumoniae, P. morganii, and several species of Haemophilus, Neisseria, Salmonella, and Staphylococcus. Chlortetracycline protects mice from infection by various strains of S. aureus with protective doses (PD50s) of 0.2-7.5 mg/kg, and from infection by E. coli (PD50 = 3 mg/kg) and K. pneumoniae (PD50 = 75 mg/kg). It acts by inhibiting protein synthesis, and it binds to a single site on the 30S ribosome subunit. Chlortetracycline is an ionophore and is selective for calcium over sodium, potassium, magnesium, strontium, and barium. It transports calcium from an aqueous phase into an organic phase environment or into multilamellar vesicles. Chlortetracycline is also a fluorescent dye that can be used to monitor calcium flux.Formal Name: (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide. CAS Number: 57-62-5. Synonyms: 7-Chlortetracycline. Molecular Formula: C22H23ClN2O8. Formula Weight: 478.9. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: Soluble, DMSO: Soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: OC([C@@](C(C(C(N)=O)=C(O)[C@H]1N(C)C)=O)(O)[C@@]1([H])C2)=C([C@@]2([H])[C@@]3(O)C)C(C4=C3C(Cl)=CC=C4O)=O. InChi Code: InChI=1S/C22H23ClN2O8/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31)/t7-,8-,15-,21-,22-/m0/s1. InChi Key: CYDMQBQPVICBEU-XRNKAMNCSA-N. Origin: Bacterium/Streptomyces sp..
Keywords: | 7-Chlortetracycline, (4S,4aS,5aS,6S,12aS)-7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide |
Supplier: | Cayman Chemical |
Supplier-Nr: | 23302 |
Properties
Application: | Broad-spectrum antibiotic, Protein biosynthesis inhibitor |
MW: | 478.9 D |
Formula: | C22H23ClN2O8 |
Purity: | >98% |
Format: | Solid |
Database Information
CAS : | 57-62-5| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Warning |
GHS Hazard Pictograms: |
|
H Phrases: | H302 |
P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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