Chlorin e6

Chlorin e6 (Ce6) is a photosensitizer. It is active against S. aureus, P. aeruginosa, E. coli, and S. typhimurium when used at a concentration of 20 µM in combination with photodynamic therapy (PDT). Ce6 (5 and 10 mg/kg) induces tumor regression when combined with PDT in several sarcoma rat xenograft models.Formal Name: (7S,8S)-3-carboxy-5-(carboxymethyl)-13-ethenyl-18-ethyl-7,8-dihydro-2,8,12,17-tetramethyl-21H,23H-porphine-7-propanoic acid. CAS Number: 19660-77-6. Synonyms: Ce6. Molecular Formula: C34H36N4O6. Formula Weight: 596.7. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml, Ethanol: slightly soluble. lambdamax: 286, 400, 501, 608, 663 nm. SMILES: CC1=C2[NH]C(/C(CC(O)=O)=C([C@@H](CCC(O)=O)[C@@H]3C)\[N]=C3/C=C4[NH]/C(C(C=C)=C\4C)=C\C5=[N]/C(C(CC)=C5C)=C\2)=C1C(O)=O. InChi Code: InChI=1S/C34H36N4O6/c1-7-19-15(3)23-12-25-17(5)21(9-10-29(39)40)32(37-25)22(11-30(41)42)33-31(34(43)44)18(6)26(38-33)14-28-20(8-2)16(4)24(36-28)13-27(19)35-23/h7,12-14,17,21,35,38H,1,8-11H2,2-6H3,(H,39,40)(H,41,42)(H,43,44)/b23-12-,24-13-,25-12-,26-1. InChi Key: VAJLRIOJDADNAT-HHGNVTQFSA-N.