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Description: cFMS Receptor Inhibitor II is a CSF1R kinase (FMS Receptor, colony stimulating factor 1 receptor, Macrophage colony-stimulating factor receptor) inhibitor with an IC50 of 2.8 nM, demonstrating significant selectivity over other kinases. This compound also exhibits notable CSF1R inhibition with an IC50 of 1.4 µM in cellular assays. Target: c-Fms. Smiles: Cc1ccc(Nc2c(cnc3cc(ccc23)-c2ccncc2)C(N)=O)cc1C. References: Buckles R E , Mock G V . THE PREPARATIO NOFTIGLICA NDANGELICA CIDSANDEST ERS\r, 1[J]. The Journal of Organic Chemistry, 1950, 15(3):680-684.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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