CFI-400437

Item number	Size	Manual	SDS	Delivery time	Price
SYN-1207-M001	1 mg	-	-	3 - 9 business days*	250.00€
SYN-1207-M005	5 mg	-	-	3 - 9 business days*	514.00€
SYN-1207-M010	10 mg	-	-	3 - 9 business days*	856.00€
SYN-1207-M050	50 mg	-	-	3 - 9 business days*	-
SYN-1207-M100	100 mg	-	-	3 - 9 business days*	-

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CFI-400437 is a potent PLK4 inhibitor (IC50=0.6nM) and selective against other members of the PLK... more

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Product information "CFI-400437"

CFI-400437 is a potent PLK4 inhibitor (IC50=0.6nM) and selective against other members of the PLK family (>10µM). Against a broad panel of kinases, only a small subset is significantly inhibited. CFI-400437 is a potent inhibitor of MCF-7, MDA-MB-468 and MDA-MB-231 cell growth and very effective in a mouse xenograft model of tumor growth.

Keywords:	(E)-5-Methoxy-3-((3-((E)-2-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)vinyl)-1H-indazol-6-yl)methylene)indolin-2-one dihydrochloride
Supplier:	SYNkinase
Supplier-Nr:	1207