Cefepime (hydrochloride hydrate)

Cefepime (hydrochloride hydrate)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay23633-250 250 mg -

6 - 10 business days*

48.00€
Cay23633-500 500 mg -

6 - 10 business days*

85.00€
Cay23633-1 1 g -

6 - 10 business days*

149.00€
Cay23633-5 5 g -

6 - 10 business days*

593.00€
 
Cefepime is a broad-spectrum cephalosporin antibiotic that inhibits the growth of Gram-positive... more
Product information "Cefepime (hydrochloride hydrate)"
Cefepime is a broad-spectrum cephalosporin antibiotic that inhibits the growth of Gram-positive and Gram-negative bacteria. It inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 µg/ml), but does not inhibit the growth of methicillin-resistant S. aureus (MRSA) or S. haemolyticus (MIC50s = >128 µg/ml). Cefepime inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = =0.12-2 µg/ml). It also inhibits the growth of E. coli and Klebsiella strains that produce extended-spectrum beta-lactamase (ESBL, MIC90s = 4 and 8 µg/mL, respectively) and of indole-positive Proteae (MIC90 = 0.25 µg/ml). Cefepime inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg). Formulations containing cefepime have been used in the treatment of a variety of bacterial infections.Formal Name: 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-pyrrolidinium, monochloride, monohydrochloride, monohydrate. CAS Number: 123171-59-5. Molecular Formula: C19H25N6O5S2 . Cl [HCl] [H2O]. Formula Weight: 571.5. Purity: >90%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 0.1 mg/ml, DMSO: 0.2 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 238, 264 nm. SMILES: O=C(O)C1=C(C[N+]2(C)CCCC2)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC)=O)([H])N1C3=O.[Cl-].Cl.O. InChi Code: InChI=1S/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11,,,/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29),2*1H,1H2/b23-12-,,,/t13-,17-,,,/m1.../s1. InChi Key: LRAJHPGSGBRUJN-OMIVUECESA-N.
Keywords: 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-pyrrolidinium, monochloride, monohydrochloride, monohydrate
Supplier: Cayman Chemical
Supplier-Nr: 23633

Properties

Application: Antibacterial, Cell wall biosynthesis inhibitor
MW: 571.5 D
Formula: C19H25N6O5S2 . Cl [HCl] [H2O]
Purity: >90%
Format: Crystalline Solid

Database Information

CAS : 123171-59-5| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H317, H318, H334
P Phrases: P261, P272, P280, P284, P302+352, P304+341, P305+351+338, P310, P321, P333+313, P342+311, P362+364, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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