Cefadroxil (hydrate)

Cefadroxil is a semisynthetic cephalosporin antibiotic. It is active against a variety of Gram-positive and Gram-negative bacteria, including B. anthracis, V. cholerae, and P. multocida strains (MICs = 1, 2, and 4 µg/ml, respectively), among others. Cefadroxil is protective against infection by strains of S. pyogenes, S. pneumoniae, or S. aureus in mice with 50% protective dose (PD50) values of 0.6-2.4, 18-24, and 0.3-29 mg/kg, respectively. Formulations containing cefadroxil have been used in the treatment of a variety of bacterial infections.Formal Name: (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, monohydrate. CAS Number: 66592-87-8. Molecular Formula: C16H17N3O5S . H2O. Formula Weight: 381.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: Methanol: slightly, sonicated, Water: slightly, heated. SMILES: OC1=CC=C([C@@H](N)C(N[C@@H]2C(N3[C@]2([H])SCC(C)=C3C(O)=O)=O)=O)C=C1.O. InChi Code: InChI=1S/C16H17N3O5S.H2O/c1-7-6-25-15-11(14(22)19(15)12(7)16(23)24)18-13(21)10(17)8-2-4-9(20)5-3-8,/h2-5,10-11,15,20H,6,17H2,1H3,(H,18,21)(H,23,24),1H2/t10-,11-,15-,/m1./s1. InChi Key: NBFNMSULHIODTC-CYJZLJNKSA-N.