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![CDPI3-CPG [Minor Groove Binder CPG] *500A*](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ABD-6900 | 100 mg | - |
3 - 8 business days* |
265.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Minor Groove Binder (MGB) molecules selectively bind to the minor groove of a DNA molecule, the... more
Product information "CDPI3-CPG [Minor Groove Binder CPG] *500A*"
Minor Groove Binder (MGB) molecules selectively bind to the minor groove of a DNA molecule, the shallow furrow in the DNA helix. MGB-labeled oligonucleotides form stable hybrid complexes with complementary DNA and RNA target sequences. Dihydropyrroloindole tripeptide (CDPI3), the analogs of natural product CC-1065, have been shown to arrest sequence-specific primer extension on single-stranded DNA when linked to oligonucleotides. CDPI3-containing oligonucleotides increases both the specificity and the strength of hybridization, thus enhancing the stability of DNA duplexes. The addition of MGB molecules to DNA probes allows the design of shorter hybridization probes useful for molecular diagnostics, e.g., quantitative PCR based assays. Several designs are possible, including Taqman MGB probes. AAT Bioquest offer this CPG support for conveniently adding an MGB moiety to the 3'-terminals of oligos. We also offer MGB phosphoramidite for labeling 5' terminus with an MGB moiety.
Supplier: | AAT Bioquest |
Supplier-Nr: | 6900 |
Properties
Application: | Quantitative PCR based assays, Hybridization stabilization |
Database Information
Handling & Safety
Storage: | -20°C (protect from light) |
Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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