Cdk1 Inhibitor

Cdk1 inhibitor is an inhibitor of Cdk1 (IC50 = 5.8 µM). It is selective for Cdk1 over Cdk5 and glycogen synthase kinase 3beta (GSK3beta, IC50s = 25 and >100 µM, respectively). It inhibits the proliferation of HeLa cells with an IC50 value of 2 µM.Formal Name: 3-[(2-chloro-1H-indol-3-yl)methylene]-1,3-dihydro-2H-indol-2-one. CAS Number: 220749-41-7. Synonyms: Cyclin-dependent Kinase 1 Inhibitor. Molecular Formula: C17H11ClN2O. Formula Weight: 294.7. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Ethanol: Soluble, Methanol: Soluble. SMILES: ClC1=C(/C=C2C(C=CC=C3)=C3NC/2=O)C4=CC=CC=C4N1. InChi Code: InChI=1S/C17H11ClN2O/c18-16-12(10-5-1-3-7-14(10)19-16)9-13-11-6-2-4-8-15(11)20-17(13)21/h1-9,19H,(H,20,21)/b13-9-. InChi Key: QJKBRWSJWQVKLY-LCYFTJDESA-N.