CAY10761

CAY10761 is an inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1, IC50s = 467 and 429 µM for the human and snake venom enzymes, respectively). It also inhibits mushroom tyrosinase (Ki = 1.9 µM) and urease from jack bean, P. mirabilis, and B. pasteurii (IC50s = 0.093, <0.125, and 0.089 mM, respectively, at pH 8.2).Formal Name: 5,5'-(1,3-propanediyl)bis-1,3,4-oxadiazole-2(3H)-thione. CAS Number: 333409-31-7. Molecular Formula: C7H8N4O2S2. Formula Weight: 244.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:4): 0.20 mg/ml. lambdamax: 266 nm. SMILES: S=C1OC(CCCC2=NNC(O2)=S)=NN1. InChi Code: InChI=1S/C7H8N4O2S2/c14-6-10-8-4(12-6)2-1-3-5-9-11-7(15)13-5/h1-3H2,(H,10,14)(H,11,15). InChi Key: XQFRUIPQODDPMN-UHFFFAOYSA-N.