CAY10410

CAY10410
Item number Size Datasheet Manual SDS Delivery time Quantity Price
TGM-T35811-500ug 500 µg -

7 - 10 business days*

217.00€
TGM-T35811-1mg 1 mg

7 - 10 business days*

395.00€
 
Description: CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with... more
Product information "CAY10410"
Description: CAY10410 is an analog of prostaglandin D2/prostaglandin J2 (PGD2/PGJ2) with structural modifications intended to give it PPARgamma ligand activity and resistance to metabolism. 15-deoxy-delta12,14-PGJ2 has been shown to be a potent ligand for PPARgamma. Metabolism of the cyclopentenone prostaglandins PGA2, PGJ2, and delta12-PGJ2 occurs via glutathione addition across the alpha,beta unsaturated enone. CAY10410 was designed as an analog of the PPARgamma-binding prostaglandins which could not undergo this conjugation reaction. In human neuroblastoma SH-SY5Y cells, CAY10410 was not cytotoxic at up to 25 µM. It also failed to covalently modify thioredoxin or induce oxidative stress at 50 µM. Target: Others. Smiles: C(\C=C/CCCCC)=C/1\[C@@H](C/C=C\CCCC(O)=O)CCC1=O
Supplier: TargetMol
Supplier-Nr: T35811

Properties

MW: 318.45 D
Formula: C20H30O3

Database Information

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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