Caspofungin diacetate

White to beige powder Soluble in DMSO (25mg/ml), DMF (20mg/ml), ehtanol (20mg/ml) or water (15mg/ml). Chemical. CAS: 179463-17-3. Formula: C52H88N10O15 · 2C2H4O2. MW: 1213.42. Caspofungin acetate is an antifungal compound that is classified as an echinocandin. It is a semi-synthetic analogue of pneumocandin B0 with improved water solubility, a significant limitation in the development of the echinocandin class as pharmaceuticals. Caspofungin acetate acts by non-competititvely inhibiting the enzyme 1,3-beta glucan synthase and preventing the synthesis of glucan and distutbing the integrity in the fungal cell wall. This agent is used in fungal cell wall biosynthesis research to study the role of beta-1,3-D-glucans in cell wall integrity and fungal survival under various environmental and chemical stresses. It is effective against disseminated or invasive aspergillosis and candidiasis in mice.