Carbendazim

Carbendazim is a carbamate fungicide and an active metabolite of benomyl (Cay-34634) and thiophanate-methyl (Cay-35402). It is also a degradation product of benomyl. Carbendazim is active against the plant pathogenic fungi N. parvum, B. dothidea, D. seriata, and L. theobromae in vitro (EC50s = 0.01-0.07 mg/L) and protects grapevines from pruning wounds caused by D. seriata or D. mutila in vivo. Carbendazim (100 µM) inhibits the growth of, and microtubule polymerization in, S. cerevisiae. It impairs meiosis and steroidogenesis in rat seminiferous tubules ex vivo and increases prostate weight in rats when administered at a dose of 100 mg/kg but does not affect other testosterone-dependent or estrogen-dependent tissues. It has been found as a contaminant in various jellies and jams and in wastewater influent and effluent. Formulations containing carbendazim have been used as preservatives for wood and other materials, as well as fungicides in agricultural and residential areas.Formal Name: N-1H-benzimidazol-2-yl-carbamic acid, methyl ester. CAS Number: 10605-21-7. Synonyms: A-118, methyl Benzimidazol-2-yl-carbamate, methyl 2-Benzimidazolecarbamate, MBC, NSC 109874, U-32104. Molecular Formula: C9H9N3O2. Formula Weight: 191.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMF:PBS(pH7.2) (1:2): 0.3 mg/ml, DMSO: 25 mg/ml, Ethanol: 5 mg/ml. lambdamax: 244, 281, 287 nm. SMILES: O=C(OC)NC1=NC2=CC=CC=C2N1. InChi Code: InChI=1S/C9H9N3O2/c1-14-9(13)12-8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H2,10,11,12,13). InChi Key: TWFZGCMQGLPBSX-UHFFFAOYSA-N.