Carbamazepine 10,11-epoxide
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Description: Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant... more
Product information "Carbamazepine 10,11-epoxide"
Description: Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine. It is formed by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes from HepG2 cells expressing CYP3A4 or CYP2C8, respectively. Carbamazepine 10,11-epoxide exhibits anticonvulsant activity against maximal electroshock-induced seizures in mice and has been detected in wastewater effluent [1][2][3]. Target: Others. Smiles: NC(=O)N1c2ccccc2C2OC2c2ccccc12. References: Kerr, B.M., Thummel, K.E., Wurden, C.J., et al.Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formationBiochem. Pharmacol.47(11)1969-1979(1994)
| Supplier: | TargetMol |
| Supplier-Nr: | T37149 |
Properties
| Application: | Carbamazepine active metabolite |
| MW: | 252.27 D |
| Formula: | C15H12N2O2 |
Database Information
| CAS : | 36507-30-9| Matching products |
| KEGG ID : | K17689 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| GHS Hazard Pictograms: |
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| H Phrases: | H411 |
| P Phrases: | P273, P391, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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