Cambinol

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
LKT-C0048.5	5 mg				3 - 8 business days*		325.00€
LKT-C0048.25	25 mg		-		3 - 8 business days*		1,348.00€

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Cambinol is an inhibitor of sirtuins, particularly sirtuin1. Cambinol exhibits anti-inflammatory... more

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Product information "Cambinol"

Cambinol is an inhibitor of sirtuins, particularly sirtuin1. Cambinol exhibits anti-inflammatory and anticancer chemotherapeutic activities. In various cell lines, cambinol suppresses MAPK and MEK signaling and inhibits expression of pro-inflammatory cytokines such as IL-1 , IL-6, TNF- , and IFN- . Additionally, cambinol improves survival of animal models of endotoxic shock and septic shock. In vitro, cambinol inhibits proliferation and increases differentiation and senescence in hepatocellular carcinoma cells. In vivo, cambinol inhibits xenograft growth in models of hepatocellular carcinoma and Burkitt's lymphoma.

Keywords:	SIRT 1/2 inhibitor IV, SIRT1 Inhibitor II, NSC112546, SIRT2 Inhibitor VI.
Supplier:	LKT Laboratories
Supplier-Nr:	C0048

Properties

Application:	SIRT1 Inhibitor
MW:	360.43 D
Formula:	C21H16N2O2S
Purity:	>98%
Format:	Solid

Database Information

CAS :	14513-15-6\| Matching products
KEGG ID :	K11411 \| Matching products

Handling & Safety

Storage:	+20°C
Shipping:	+20°C (International: +20°C)
Signal Word:	Warning
GHS Hazard Pictograms:
H Phrases:	H302
P Phrases:	P264, P270, P330, P301+P312, P501