Cabozantinib
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that... more
Product information "Cabozantinib"
Description: Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM). Cabozantinib exhibits both antitumor and antiangiogenic activity. Target: c-RET, c-Met/HGFR, Apoptosis, FLT, c-Kit, TAM Receptor, VEGFR. Smiles: C(NC1=CC=C(OC=2C3=C(C=C(OC)C(OC)=C3)N=CC2)C=C1)(=O)C4(C(NC5=CC=C(F)C=C5)=O)CC4. References: Dai J, et al. Cabozantinib inhibits prostate cancer growth and prevents tumor-induced bone lesions. Clin Cancer Res. 2014 Feb 1,20(3):617-30.
| Keywords: | XL184, BMS-907351 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2586 |
Properties
| Application: | Targets kinase insert domain protein receptor [EC:2.7.10.1] (KDR, VEGFR2, CD309) |
| MW: | 501.51 D |
| Formula: | C28H24FN3O5 |
Database Information
| CAS : | 849217-68-1| Matching products |
| KEGG ID : | K05098 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H318 |
| P Phrases: | P264, P280, P310, P321, P302+P352, P305+P351+P338, P332+P313, P362+P364 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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