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Description: BRD4 Inhibitor-27 is a potent BRD4 inhibitor that inhibits BRD4 BD1 and BRD4 BD2 with IC50s of 9.6 and 11.3 µM, respectively.BRD4 Inhibitor-27 has anticancer activity and can be used for breast cancer research. Target: Epigenetic Reader Domain. Smiles: FC(F)(F)C1=NN=C2C=CC(NCCC3=CNC4=C3C=CC=C4)=NN12. References: Kim JH, et al. Crystal structure of [1,2,4] triazolo[4,3- b ]pyridazine derivatives as BRD4 bromodomain inhibitors and structure-activity relationship study . Sci Rep 13, 10805 (2023).
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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