Branaplam hydrochloride

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T62381-2mg	2 mg				7 - 10 business days*		54.00€

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Description: Branaplam (LMI070, NVS-SM1) hydrochloride is a selective, orally active SMN2... more

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Product information "Branaplam hydrochloride"

Description: Branaplam (LMI070, NVS-SM1) hydrochloride is a selective, orally active SMN2 splicing modulator that acts on SMN (EC50: 20 nM) and inhibits hERG (IC50: 6.3 µM). In a mouse model of severe spinal muscular atrophy (SMA), Branaplam hydrochloride increased full-length SMN protein and improved survival. Target: Others. Smiles: Cl.CC1(C)CC(CC(C)(C)N1)Oc1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1

Supplier:	TargetMol
Supplier-Nr:	T62381

Properties

Application:	Targets survival motor neuron protein (SMN)
MW:	429.95 D
Formula:	C22H28ClN5O2

Database Information

CAS :	1562338-39-9\| Matching products
KEGG ID :	K13129 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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