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![bpV(phen) (potassium hydrate)](https://www.biomol.com/media/image/34/a6/76/Cay13331-5_600x600.png)
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay13331-5 | 5 mg | - |
6 - 10 business days* |
49.00€
|
|||
Cay13331-25 | 25 mg | - |
6 - 10 business days* |
234.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
bpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine... more
Product information "bpV(phen) (potassium hydrate)"
bpV(phen) is a bisperoxovanadium (bpV) compound which inhibits several different protein tyrosine phosphatases (PTPs), with selectivity for PTEN (IC50 = 38 nM). It also inhibits the vascular endothelial PTP, PTP-beta (IC50 = 343 nM), and PTP-1beta (IC50 = 920 nM). At 0.1 mM, bpV(phen) inhibits SH2 domain-containing inositol 5'-phosphatase-2. Presumably by inhibiting insulin receptor kinase-associated PTPs, bpV(phen) activates the insulin receptor tyrosine kinase and promotes downstream signaling, including activation of PI3-kinase.Formal Name: (PB-7-23-111'1'3)-oxodiperoxy(1,10-phenanthroline-kappaN1,kappaN10)-vanadate(1-), potassium trihydrate. CAS Number: 171202-16-7. Synonyms: Bisperoxovanadium(phen), Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V). Molecular Formula: C12H8N2O5V . K+(H2O)3. Formula Weight: 404.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 1 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 224, 272 nm. SMILES: O=[V+3]12([N]3=CC=C4)([O-][O-]1)([O-][O-]2)[N]5=C6C3=C4C=CC6=CC=C5.O.O.O.[K+]. InChi Code: InChI=1S/C12H8N2.K.2O2.3H2O.O.V/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1,,2*1-2,,,,,/h1-8H,,,,3*1H2,,/q,+1,2*-2,,,,,+3. InChi Key: TYPQOCBUPQJDHB-UHFFFAOYSA-N.
Keywords: | Bisperoxovanadium(phen), Potassium Bisperoxo(1,10-phenanthroline) oxovanadate (V), (PB-7-23-111'1'3)-oxodiperoxy(1,10-phenanthroline-kappaN1,kappaN10)-vanadate(1-), potassium trihydrate |
Supplier: | Cayman Chemical |
Supplier-Nr: | 13331 |
Properties
Application: | PTP inhibitor |
MW: | 404.3 D |
Formula: | C12H8N2O5V . K+(H2O)3 |
Purity: | >98% |
Format: | Crystalline Solid |
Database Information
CAS : | 171202-16-7| Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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