Bisphenol A-beta-D-Glucuronide

Bisphenol A-beta-D-glucuronide (BPA-glucuronide) is an inactive metabolite of the plasticizer BPA. It is formed from BPA primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT2B15. Unlike BPA, BPA-glucuronide does not bind to estrogen receptors (ERs) in cell-free assays or induce ER-mediated transcription in a reporter assay using MCF-7 cells. BPA-glucuronide blood levels are lower in patients with Parkinson's disease compared to individuals without Parkinson's disease with the same blood levels of total BPA, which includes BPA and BPA-glucuronide.Formal Name: beta-D-glucopyranosiduronic acid, 4-[1-(4-hydroxyphenyl)-1-methylethyl]phenyl. CAS Number: 267244-08-6. Synonyms: BPA-glucuronide, BPA-beta-D-glucuronide, BPA-monoglucuronide, BPAG. Molecular Formula: C21H24O8. Formula Weight: 404.4. Purity: >95%. Formulation: (Request formulation change), A solution in methanol. Solubility: Methanol: Slightly soluble: 0.1-1 mg/ml. SMILES: O[C@H]([C@H]1O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)OC(C=C2)=CC=C2C(C)(C(C=C3)=CC=C3O)C.O[C@H]([C@H]4O)[C@@H](O[C@@H]([C@H]4O)C(O)=O)OC(C=C5)=CC=C5C(C)(C(C=C6)=CC=C6O)C. InChi Code: InChI=1S/2C21H24O8/c2*1-21(2,11-3-7-13(22)8-4-11)12-5-9-14(10-6-12)28-20-17(25)15(23)16(24)18(29-20)19(26)27/h2*3-10,15-18,20,22-25H,1-2H3,(H,26,27)/t2*15-,16-,17+,18-,20+/m00/s1. InChi Key: NOSNTNKVRFNMDK-UQFQXFSJSA-N.