Biotin-PEG3-azide

Biotin-PEG3-azide is a PEGylated version of biotin-azide (Cay-13040) that is more hydrophilic due to the incorporation of a PEGylated spacer. It can be used to label terminal alkynes via copper-catalyzed click reactions or copper-free click reactions with cyclooctynes., Biotin-PEG3-azide has been used to non-enzymatically and covalently tag proteins, which can be separated and detected using common laboratory methods such as SDS-PAGE and Western blot. It can be used in combination with other protein tags. Biotin-PEG3-azide has also been used in nanostructured biointerfaces to study ligand and receptor spacing when there are different signaling molecules present.Formal Name: (3aS,4S,6aR)-N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide. CAS Number: 875770-34-6. Synonyms: Azide-PEG3-biotin, Click Tag(TM) Biotin-PEG3-azide. Molecular Formula: C18H32N6O5S. Formula Weight: 444.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O=C1N[C@@]2([H])[C@@](CS[C@H]2CCCCC(NCCOCCOCCOCCN=[N+]=[N-])=O)([H])N1. InChi Code: InChI=1S/C18H32N6O5S/c19-24-21-6-8-28-10-12-29-11-9-27-7-5-20-16(25)4-2-1-3-15-17-14(13-30-15)22-18(26)23-17/h14-15,17H,1-13H2,(H,20,25)(H2,22,23,26)/t14-,15-,17-/m0/s1. InChi Key: ZWFOOMQCYIGZBE-ZOBUZTSGSA-N.