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Description: BI605906 is an IKKbeta inhibitor that inhibits tumor necrosis factor alpha-dependent IkappaB degradation and expression of the pro-inflammatory mediator interleukin-6, which can be used to study inflammatory skin diseases such as psoriasis. Target: IkappaB/IKK, IL Receptor. Smiles: CCC(F)(F)c1cc(nc2sc(C(N)=O)c(N)c12)N1CCC(CC1)S(C)(=O)=O. References: Clark K, et al. Novel cross-talk within the IKK family controls innate immunity. Biochem J. 2011 Feb 15,434(1):93-104.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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