BI-882370

Item number	Size	Delivery time	Price
TGM-TQ0048-1mg	1 mg	7 - 10 business days*	37.00€
TGM-TQ0048-2mg	2 mg	7 - 10 business days*	52.00€
TGM-TQ0048-5mg	5 mg	7 - 10 business days*	77.00€
TGM-TQ0048-10mg	10 mg	7 - 10 business days*	136.00€
TGM-TQ0048-25mg	25 mg	7 - 10 business days*	245.00€
TGM-TQ0048-50mg	50 mg	7 - 10 business days*	443.00€

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Description: BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic... more

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Product information "BI-882370"

Description: BI-882370 is a specific RAF kinase inhibitor. BI-882370 inhibits the oncogenic BRAFV600E-mutant, the WT BRAF and CRAF kinases (IC50s: 0.4, 0.8 and 0.6 nM). BI-882370 also inhibits SRC family kinases. Target: Raf. Smiles: CCCS(=O)(=O)Nc1ccc(F)c(c1F)-n1cc(-c2cncnc2)c2nc(ccc12)N(C)C1CCN(CC)CC1. References: Waizenegger IC, et al. A Novel RAF Kinase Inhibitor with DFG-Out-Binding Mode: High Efficacy in BRAF-Mutant Tumor Xenograft Models in the Absence of Normal Tissue Hyperproliferation. Mol Cancer Ther. 2016 Mar,15(3):354-65.

Supplier:	TargetMol
Supplier-Nr:	TQ0048

Properties

Application:	RAF inhibitor
MW:	569.67 D
Formula:	C28H33F2N7O2S

Database Information

CAS :	1392429-79-6\| Matching products
KEGG ID :	K04366 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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