(±)-beta-Hydroxybutyrate

(±)-beta-Hydroxybutyrate (betaOHB) is an endogenous and specific inhibitor of class I histone deacetylases (HDACs), increasing acetylation of histones in a dose-dependent manner. It does not increase acetylation of alpha-tubulin, indicating that it does not inhibit the class IIb HDAC6. Fasting or caloric restriction, two conditions associated with increased betaOHB abundance, increases global histone acetylation in mouse tissues.Formal Name: 3-hydroxy-butanoic acid. CAS Number: 300-85-6. Synonyms: 3-Hydroxybutyric Acid, NSC 3806, betaOHB. Molecular Formula: C4H8O3. Formula Weight: 104.1. Purity: >95%. Formulation: (Request formulation change), Neat oil. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 210 nm. SMILES: CC(O)CC(O)=O. InChi Code: InChI=1S/C4H8O3/c1-3(5)2-4(6)7/h3,5H,2H2,1H3,(H,6,7)/t3-/m. InChi Key: WHBMMWSBFZVSSR-UHFFFAOYSA-N.