Benzoylmesaconine

Benzoylmesaconine is an alkaloid that has been found in A. carmichaelii and has diverse biological activities. It promotes isolated rat liver mitochondrial energy metabolism (EC50 = 30.95 µg/ml). Benzoylmesaconine (1 µg/kg) increases survival in a mouse model of burn-associated herpes simplex virus type 1 (HSV1) infection from 5 to 90%. It also increases the latency to tail withdrawal or a struggling response in a tail pressure test in mice (ED50 = 38.9 mg/kg).Formal Name: 1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)-20-methyl-aconitane-3alpha,8,13,14alpha,15alpha-pentol, 14-benzoate. CAS Number: 63238-67-5. Synonyms: 14-Benzoylmesaconine. Molecular Formula: C31H43NO10. Formula Weight: 589.7. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml, Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml. lambdamax: 228 nm. SMILES: CO[C@@H](C[C@H]1O)C([C@@](C[C@@]2([C@H]3OC)O)([H])[C@H](C2([H])OC(C4=CC=CC=C4)=O)[C@@]5([C@H]3O)O)(C6C5[C@@H]7OC)[C@@]7([H])[C@]1(COC)CN6C. InChi Code: InChI=1S/C31H43NO10/c1-32-13-28(14-38-2)17(33)11-18(39-3)30-16-12-29(36)25(42-27(35)15-9-7-6-8-10-15)19(16)31(37,24(34)26(29)41-5)20(23(30)32)21(40-4)22(28)30/h6-10,16-26,33-34,36-37H,11-14H2,1-5H3/t16-,17-,18+,19-,20?,21+,22-,23?,24+,25?,26+,28+,29-,30?,31-/m1/s1. InChi Key: PULWZCUZNRVAHT-DKDANLFQSA-N. Origin: Plant/Aconitum carmichaelii.