Benazeprilat

Description: Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combination with other classes of compounds, including thiazide diuretics and calcium channel blockers, to reduce the incidence of diseases associated with cardiovascular risk and secondary end-organ damage.Benazeprilat may be be used to study acute left ventricular failure. Target: RAAS, Endogenous Metabolite. Smiles: C(C(O)=O)N1C=2C(CC[C@H](N[C@@H](CCC3=CC=CC=C3)C(O)=O)C1=O)=CC=CC2. References: Barrios V, et al. Antihypertensive and organ-protective effects of benazepril. Expert Rev Cardiovasc Ther. 2010 Dec,8(12):1653-71.