Bafilomycin A1
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase... more
Product information "Bafilomycin A1"
Description: Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase inhibitor (IC50=0.44 nM) that is specific and reversible. Bafilomycin A1 is an inhibitor of the late phase of autophagy, blocking the fusion of autophagosomes with lysosomes. Bafilomycin A1 also induces apoptosis. Target: Antibacterial, Apoptosis, Autophagy, Antibiotic, Proton pump. Smiles: [H][C@@]1(OC(=O)\C(OC)=C\C(\C)=C\[C@@H](C)[C@@H](O)[C@@H](C)C\C(C)=C\C=C\[C@@H]1OC)[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O)[C@H](C)[C@H](O1)C(C)C. References: Ohta T, et al. Bafilomycin A1 induces apoptosis in the human pancreatic cancer cell line Capan-J Pathol. 1998 Jul,185(3):324-30.
| Supplier: | TargetMol |
| Supplier-Nr: | T6740 |
Properties
| Application: | V-ATPase inhibitor |
| MW: | 622.83 D |
| Formula: | C35H58O9 |
Database Information
| CAS : | 88899-55-2| Matching products |
| KEGG ID : | K02146 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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