(+)-Baclofen (hydrochloride)

(+)-Baclofen is a GABAB receptor agonist. In vivo, (+)-baclofen (1 and 3 mg/kg) increases latency to paw or tail withdrawal in the hot-plate test in mice. (+)-Baclofen (3 mg/kg) also reduces the number of lever responses for alcohol in Sardinian alcohol-preferring rats.Formal Name: betaR-(aminomethyl)-4-chloro-benzenepropanoic acid, monohydrochloride. CAS Number: 63701-55-3. Synonyms: (R)-Baclofen. Molecular Formula: C10H12ClNO2 . HCl. Formula Weight: 250.1. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 220 nm. SMILES: OC(C[C@H](C1=CC=C(C=C1)Cl)CN)=O.Cl. InChi Code: InChI=1S/C10H12ClNO2.ClH/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14,/h1-4,8H,5-6,12H2,(H,13,14),1H/t8-,/m0./s1. InChi Key: WMNUVYYLMCMHLU-QRPNPIFTSA-N.