AZD-8055
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It... more
Product information "AZD-8055"
Description: AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms. Target: Apoptosis, mTOR, Autophagy. Smiles: C[C@@H]1N(C=2C3=C(N=C(N2)N4[C@@H](C)COCC4)N=C(C=C3)C5=CC(CO)=C(OC)C=C5)CCOC1. References: Chresta CM, et al. AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mammalian target of rapamycin kinase inhibitor with in vitro and in vivo antitumor activity. Cancer Res, 2010, 70(1), 288-298.
| Supplier: | TargetMol |
| Supplier-Nr: | T1859 |
Properties
| Application: | mTOR kinase inhibitor |
| MW: | 465.54 D |
| Formula: | C25H31N5O4 |
Database Information
| CAS : | 1009298-09-2| Matching products |
| KEGG ID : | K07203 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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