AZD 7325
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
AZD 7325 is a positive allosteric modulator of alpha2- and alpha3 subunit-containing GABAA... more
Product information "AZD 7325"
AZD 7325 is a positive allosteric modulator of alpha2- and alpha3 subunit-containing GABAA receptors and a neutral antagonist for alpha1 subunit-containing GABAA receptors. It binds to GABAA receptors in membranes from Sf9 cells expressing alpha2beta3gamma2 subunit-containing receptors (Ki = 0.309 nM). AZD 7325 (1 mg/kg) increases marble-burying behavior, indicating anxiety-like activity, and decreases audiogenic seizure severity in the Fmr1-/- mouse model of fragile X syndrome.Formal Name: 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propyl-3-cinnolinecarboxamide. CAS Number: 942437-37-8. Synonyms: BAER-101. Molecular Formula: C19H19FN4O2. Formula Weight: 354.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble. lambdamax: 220, 345 nm. SMILES: O=C(C1=C(N)C2=CC=CC(C3=C(OC)C=CC=C3F)=C2N=N1)NCCC. InChi Code: InChI=1S/C19H19FN4O2/c1-3-10-22-19(25)18-16(21)12-7-4-6-11(17(12)23-24-18)15-13(20)8-5-9-14(15)26-2/h4-9H,3,10H2,1-2H3,(H2,21,23)(H,22,25). InChi Key: KYDURMHFWXCKMW-UHFFFAOYSA-N.
| Keywords: | BAER-101, 4-amino-8-(2-fluoro-6-methoxyphenyl)-N-propyl-3-cinnolinecarboxamide |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 36449 |
Properties
| Application: | Alpha2- / alpha3 subunit-containing GABAA receptor positive allosteric modulator |
| MW: | 354.4 D |
| Formula: | C19H19FN4O2 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 942437-37-8| Matching products |
| KEGG ID : | K05175 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed