AZ32
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: AZ32 is an orally bioavailable, blood-brain barrier-penetrating ATM inhibitor with... more
Product information "AZ32"
Description: AZ32 is an orally bioavailable, blood-brain barrier-penetrating ATM inhibitor with an IC50 of <6.2 nM for the ATM enzyme and an IC50 of 0.31 µM for ATM in cells. Target: ATM/ATR. Smiles: CNC(=O)c1ccc(cc1)-c1cnc2cnc(cn12)-c1ccccc1. References: Karlin J, et al. Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice. Mol Cancer Ther. 2018 Aug,17(8):1637-1647.
| Supplier: | TargetMol |
| Supplier-Nr: | T4443 |
Properties
| Application: | ATM inhibitor |
| MW: | 328.37 D |
| Formula: | C20H16N4O |
Database Information
| CAS : | 2288709-96-4| Matching products |
| KEGG ID : | K04728 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P301+310, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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