AZ10606120 dihydrochloride

Item number	Size	Delivery time	Price
TGM-T14366-1mg	1 mg	7 - 10 business days*	60.00€
TGM-T14366-5mg	5 mg	7 - 10 business days*	147.00€
TGM-T14366-1mL	1 ml	7 - 10 business days*	161.00€
TGM-T14366-10mg	10 mg	7 - 10 business days*	237.00€
TGM-T14366-25mg	25 mg	7 - 10 business days*	477.00€
TGM-T14366-50mg	50 mg	7 - 10 business days*	687.00€

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Description: AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor... more

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Product information "AZ10606120 dihydrochloride"

Description: AZ10606120 dihydrochloride is a selectable, potent, high-affinity receptor antagonist with K D values of 1.4 and 19 nM at human and rat P2X 7 receptors, respectively. AZ10606120 dihydrochloride inhibits tumor growth and has anti-angiogenic activity. AZ 10606120 acts as a negative allosteric modulator when bound to a site coupled to the ATP binding site. Target: P2X Receptor. Smiles: Cl.Cl.OCCNCCNc1ccc2c(NC(=O)CC34CC5CC(CC(C5)C3)C4)cccc2n1. References: Allsopp RC, et al. Unique residues in the ATP gated human P2X7 receptor define a novel allosteric binding pocket for the selective antagonist AZ10606120. Sci Rep. 2017 Apr 7,7(1):725.

Supplier:	TargetMol
Supplier-Nr:	T14366

Properties

Application:	P2X7 receptor antagonist
MW:	495.48 D
Formula:	C25H36Cl2N4O2

Database Information

CAS :	607378-18-7\| Matching products
KEGG ID :	K05220 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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