Avasimibe
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A:... more
Product information "Avasimibe"
Description: Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 µM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenzymes CYP2C9/1A2/2C19 (IC50: 2.9/13.9/26.5 µM). Target: Acyltransferase, P450. Smiles: CC(C)c1cc(C(C)C)c(CC(=O)NS(=O)(=O)Oc2c(cccc2C(C)C)C(C)C)c(c1)C(C)C. References: Lee HT, et al. J Med Chem, 1996, 39(26), 5031-5034.
| Keywords: | CI-1011, PD-148515 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2753 |
Properties
| Application: | Targets sterol O-acyltransferase [EC:2.3.1.26] (SOAT) |
| MW: | 501.72 D |
| Formula: | C29H43NO4S |
Database Information
| CAS : | 166518-60-1| Matching products |
| KEGG ID : | K00637 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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