AT9283

Item number	Size	Manual	Delivery time	Price
SYN-1011-M001	1 mg	-	3 - 9 business days*	106.00€
SYN-1011-M005	5 mg	-	3 - 9 business days*	198.00€
SYN-1011-M010	10 mg	-	3 - 9 business days*	329.00€
SYN-1011-M050	50 mg	-	3 - 9 business days*	975.00€
SYN-1011-M100	100 mg	-	3 - 9 business days*	-

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Soluble in DMSO or ethanol. Aurora kinases play a key role in the regulation of mitosis and in... more

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Product information "AT9283"

Soluble in DMSO or ethanol. Aurora kinases play a key role in the regulation of mitosis and in recent years have become attractive targets for the treatment of cancer. AT9283 is a powerful inhibitor of Aurora A and B kinases as well as several other important kinases including JAK2 and Abl (T315I). AT9283 has also been shown effective in mouise xenograft models and has been studied as a possible clinical candidate. Effective IC(50) doses for Aurora kinases are in the low 2-3nM range, and inhibition of a number of other kinases including JAK2 has been reported at 1-10nM. Target: Aurora , Kinase Group: Other , Substrate: Serine-Threonine

Keywords:	AT-9283
Supplier:	SYNkinase
Supplier-Nr:	1011

Properties

Application:	Aurora inhibitor
MW:	381,4 D
Formula:	C19H23N7O2
Purity:	>95%
Format:	Solid

Database Information

CAS :	896466-04-9\| Matching products
KEGG ID :	K11481 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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