AST 487

Item number	Size	Manual	Delivery time	Price
TGM-T4053-1mg	1 mg	-	7 - 10 business days*	32.00€
TGM-T4053-2mg	2 mg	-	7 - 10 business days*	44.00€
TGM-T4053-5mg	5 mg	-	7 - 10 business days*	71.00€
TGM-T4053-1mL	1 ml	-	7 - 10 business days*	82.00€
TGM-T4053-10mg	10 mg	-	7 - 10 business days*	119.00€
TGM-T4053-25mg	25 mg	-	7 - 10 business days*	192.00€
TGM-T4053-50mg	50 mg	-	7 - 10 business days*	364.00€
TGM-T4053-100mg	100 mg	-	7 - 10 business days*	544.00€
TGM-T4053-500mg	500 mg	-	7 - 10 business days*	1,196.00€

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Description: AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation... more

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Product information "AST 487"

Description: AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3. Target: VEGFR, c-Kit, FLT, c-RET, Bcr-Abl. Smiles: C(C1=C(C(F)(F)F)C=C(NC(NC2=CC=C(OC=3C=C(NC)N=CN3)C=C2)=O)C=C1)N4CCN(CC)CC4. References: Akeno-Stuart N, et al. The RET Kinase Inhibitor NVP-AST487 Blocks Growth and Calcitonin Gene Expression through Distinct Mechanisms in Medullary Thyroid Cancer Cells. Cancer Res. 2007 Jul 15,67(14):6956-64.

Keywords:	NVP-AST 487
Supplier:	TargetMol
Supplier-Nr:	T4053

Properties

Application:	RET inhibitor
MW:	529.56 D
Formula:	C26H30F3N7O2

Database Information

CAS :	630124-46-8\| Matching products
KEGG ID :	K05126 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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