ARV-825

Item number	Size	Delivery time	Price
TGM-T5434-1mg	1 mg	7 - 10 business days*	60.00€
TGM-T5434-5mg	5 mg	7 - 10 business days*	145.00€
TGM-T5434-10mg	10 mg	7 - 10 business days*	176.00€
TGM-T5434-25mg	25 mg	7 - 10 business days*	271.00€
TGM-T5434-50mg	50 mg	7 - 10 business days*	371.00€
TGM-T5434-100mg	100 mg	7 - 10 business days*	555.00€

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Description: ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits... more

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Product information "ARV-825"

Description: ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested. Target: Epigenetic Reader Domain, PROTACs. Smiles: CC=1C2=C(N3C([C@H](CC(NC4=CC=C(OCCOCCOCCO CCNC5=C6C(C(=O)N(C6=O)C7C(=O)NC(=O)CC7)=CC=C5)C=C4)=O)N=C2C8=CC=C(Cl)C=C8)=NN=C3C)SC1C. References: Lu J, et al. Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4. Chem Biol. 2015 Jun 18,22(6):755-63.

Supplier:	TargetMol
Supplier-Nr:	T5434

Properties

Application:	Protac(R) reagent
MW:	923.43 D
Formula:	C46H47ClN8O9S

Database Information

CAS :	1818885-28-7\| Matching products
KEGG ID :	K11793 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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