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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay39615-1 | 1 mg | - |
6 - 10 business days* |
683.00€
|
|||
| Cay39615-5 | 5 mg | - |
6 - 10 business days* |
3,077.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ARN25062 is a derivative of ARN22089, an inhibitor of the protein-protein interaction between... more
Product information "ARN25062"
ARN25062 is a derivative of ARN22089, an inhibitor of the protein-protein interaction between Cdc42 and p21-activated kinase (PAK). It inhibits the proliferation of SKM28, SK-MEL-3, WM3248, and A375 melanoma cells (IC50s = 6.1, 4.6, 9.3, and 5.1 µM, respectively) and SW480 colon cancer cells (IC50 = 5.9 µM). ARN25062 (10 mg/kg) reduces tumor growth in a patient-derived xenograft (PDX) mouse model.Formal Name: 6-phenyl-2-(4-piperidinyl)-N-[3-(trifluoromethyl)phenyl]-4-pyrimidinamine. CAS Number: 3036492-85-7. Molecular Formula: C22H21F3N4. Formula Weight: 398.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly Soluble: 0.1-1 mg/ml, DMSO: Sparingly Soluble: 1-10 mg/ml. SMILES: FC(F)(F)C1=CC=CC(NC2=CC(C3=CC=CC=C3)=NC(C4CCNCC4)=N2)=C1. InChi Code: InChI=1S/C22H21F3N4/c23-22(24,25)17-7-4-8-18(13-17)27-20-14-19(15-5-2-1-3-6-15)28-21(29-20)16-9-11-26-12-10-16/h1-8,13-14,16,26H,9-12H2,(H,27,28,29). InChi Key: NGGORHPZMJVKNU-UHFFFAOYSA-N.
| Keywords: | 6-phenyl-2-(4-piperidinyl)-N-[3-(trifluoromethyl)phenyl]-4-pyrimidinamine |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 39615 |
Properties
| Application: | ARN22089 (Cdc42--p21-activated kinase interaction inhibitor) derivative |
| MW: | 398.4 D |
| Formula: | C22H21F3N4 |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 3036492-85-7| Matching products |
| KEGG ID : | K04393 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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