Aramchol

Description: Aramchol (C20-FABAC), also known as arachidyl amido cholanoic acid, is a conjugate of arachidic acid and cholic acid. It reduces ex vivo cholesterol crystallization in native human bile and dissolves pre-formed cholesterol crystals in a dose-dependent manner. Target: Others. Smiles: [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)C[C@]2([H])C[C@H](CC[C@]12C)NC(=O)CCCCCCCCCC CCCCCCCCC. References: Safadi R , Konikoff F M , Mahamid M , et al. The Fatty Acid-Bile Acid Conjugate Aramchol Reduces Liver Fat Content in Patients With Nonalcoholic Fatty Liver Disease[J]. Clinical Gastroenterology and Hepatology, 2014, 12(12):2085-2091.e1.