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Araloside A is a triterpenoid saponin that has been found in A. taibaiensis and has anti-inflammatory and gastroprotective effects. It increases apoptosis of and decreases production of IL-1beta and IL-6 in human MH7A rheumatoid arthritis fibroblast-like synoviocytes when used at concentrations ranging from 4 to 16 µM. Araloside A (50 and 100 mg/kg) reduces gastric acid secretion and lesion size in rat models of hydrochloric acid and ethanol-, aspirin-, water immersion stress-, or pyloric ligation-induced ulcer formation.Formal Name: (3beta)-28-(beta-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl 4-O-alpha-L-arabinofuranosyl-beta-D-glucopyranosiduronic acid. CAS Number: 7518-22-1. Synonyms: Chikusetsusaponin 4, Chikusetsusaponin IV, Oleanoside E. Molecular Formula: C47H74O18. Formula Weight: 927.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 5 mg/ml. SMILES: OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC([C@]2([C@@]3([H])CC(C)(C)CC2)CC[C@]4(C)C3=CC[C@@]5([H])[C@@]4(C)CC[C@]6([H])[C@]5(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@@H]8O[C@@H](CO)[C@H](O)[C@H]8O)[C@@H](C(O)=O)O7)C6(C)C)=O)O1. InChi Code: InChI=1S/C47H74O18/c1-42(2)14-16-47(41(59)65-39-33(55)30(52)28(50)23(19-48)61-39)17-15-45(6)21(22(47)18-42)8-9-26-44(5)12-11-27(43(3,4)25(44)10-13-46(26,45)7)62-40-34(56)31(53)35(36(64-40)37(57)58)63-38-32(54)29(51)24(20-49)60-38/h8,22-36,38-40,48-56H,9-20H2,1-7H3,(H,57,58)/t22-,23+,24-,25-,26+,27-,28+,29-,30-,31+,32+,33+,34+,35-,36-,38-,39-,40+,44-,45+,46+,47-/m0/s1. InChi Key: KQSFNXMDCOFFGW-GNDIVNLPSA-N. Origin: Plant/Aralia chinensis.
Keywords:
Chikusetsusaponin 4, Chikusetsusaponin IV, Oleanoside E, (3beta)-28-(beta-D-glucopyranosyloxy)-28-oxoolean-12-en-3-yl 4-O-alpha-L-arabinofuranosyl-beta-D-glucopyranosiduronic acid
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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