APY29

Item number	Size	Manual	Delivery time	Price
TGM-T3654-2mg	2 mg	-	7 - 10 business days*	36.00€
TGM-T3654-5mg	5 mg	-	7 - 10 business days*	58.00€
TGM-T3654-1mL	1 ml	-	7 - 10 business days*	64.00€
TGM-T3654-10mg	10 mg	-	7 - 10 business days*	95.00€
TGM-T3654-25mg	25 mg	-	7 - 10 business days*	182.00€
TGM-T3654-50mg	50 mg	-	7 - 10 business days*	310.00€
TGM-T3654-100mg	100 mg	-	7 - 10 business days*	560.00€
TGM-T3654-500mg	500 mg	-	7 - 10 business days*	1,167.00€

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Description: APY29 is an allosteric modulator of IRE1alpha, inhibits IRE1alpha... more

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Product information "APY29"

Description: APY29 is an allosteric modulator of IRE1alpha, inhibits IRE1alpha autophosphorylation (IC50 = 280 nM) and activates IRE1alpha RNase activity. Target: IRE1. Smiles: C1CC1c1cc(Nc2ccnc(Nc3ccc4nc[nH]c4c3)n2)n[nH]1. References: Wang, L., Perera, B., Hari, S., Bhhatarai, B., Backes, B., & Seeliger, M. et al. (2012). Divergent allosteric control of the IRE1alpha endoribonuclease using kinase inhibitors. Nature Chemical Biology, 8(12), 982-989. doi: 10.1038/nchembio.1094

Supplier:	TargetMol
Supplier-Nr:	T3654

Properties

Application:	IRE1alpha modulator
MW:	332.36 D
Formula:	C17H16N8

Database Information

CAS :	1216665-49-4\| Matching products
KEGG ID :	K08852 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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