Apremilast
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM)... more
Product information "Apremilast"
Description: Apremilast (CC-10004) (CC-10004) is a potent and orally active PDE4 (IC50=74 nM) with anti-inflammation activities. Target: PDE, TNF, Apoptosis. Smiles: [C@H](CS(C)(=O)=O)(N1C(=O)C=2C(C1=O)=CC=CC2NC(C)=O)C3=CC(OCC)=C(OC)C=C3. References: Perez-Aso M, et al. Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Arthritis Res Ther. 2015 Sep 15,17:249.
| Keywords: | CC-10004 |
| Supplier: | TargetMol |
| Supplier-Nr: | T2923 |
Properties
| Application: | Targets cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] (PDE4) |
| MW: | 460.5 D |
| Formula: | C22H24N2O7S |
Database Information
| CAS : | 608141-41-9| Matching products |
| KEGG ID : | K13293 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H317 |
| P Phrases: | P261, P264, P270, P272, P280, P321, P330, P301+P310, P302+P352, P333+P313, P362+P364, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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