AMG-47a

Item number	Size	Delivery time	Price
TGM-T7123-1mg	1 mg	7 - 10 business days*	40.00€
TGM-T7123-5mg	5 mg	7 - 10 business days*	88.00€
TGM-T7123-1mL	1 ml	7 - 10 business days*	97.00€
TGM-T7123-10mg	10 mg	7 - 10 business days*	154.00€
TGM-T7123-25mg	25 mg	7 - 10 business days*	261.00€
TGM-T7123-50mg	50 mg	7 - 10 business days*	387.00€
TGM-T7123-100mg	100 mg	7 - 10 business days*	571.00€

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Description: AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote... more

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Product information "AMG-47a"

Description: AMG-47a is a potent inhibitor of Lck and T cell proliferation. AMG-47a could promote the degradation of the KRAS oncoprotein. AMG-47a selectively reduced the levels of EGFP-KRASG12V protein but did not affect EGFP protein in cells. Target: JAK, VEGFR, p38 MAPK, Src. Smiles: Cc1ccc(cc1-c1ccc2nc(NCCN3CCOCC3)ncc2c1)C(=O)Nc1cccc(c1)C(F)(F)F. References: Carver J , Dexheimer T S , Hsu D , et al. A High-Throughput Assay for Small Molecule Destabilizers of the KRAS Oncoprotein[J]. Plos One, 2014, 9(8):e103836.

Supplier:	TargetMol
Supplier-Nr:	T7123

Properties

Application:	Lck/VEGFR2/p38alpha/JAK3 inhibitor
MW:	535.56 D
Formula:	C29H28F3N5O2

Database Information

CAS :	882663-88-9\| Matching products
KEGG ID :	K05856 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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