Ambuic Acid

Ambuic Acid
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay27483-500 500 µg - -

6 - 10 business days*

161.00€
Cay27483-1 1 mg - -

6 - 10 business days*

306.00€
 
Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species... more
Product information "Ambuic Acid"
Ambuic acid is a cyclohexanone originally isolated from Pestalotiopsis and Monochaetia species that has phytopathogenic antifungal, quorum sensing inhibitory, and antibacterial activities. It is active against P. ultimum (MIC = 7.5 µg/ml) and inhibits the growth of a variety of other phytopathogenic fungi, including F. solani, H. sativum, and C. gramineum, but not P. oryzae, R. solani, or B. cinerea. Ambuic acid inhibits the biosynthesis of cyclic peptides involved in quorum sensing, including gelatinase biosynthesis-activating pheromone (GBAP) in E. faecalis, autoinducing peptide I (AIP-I) in S. aureus, and LsrD698 and LsrD826 in L. innocua. It suppresses abcess formation in a mouse model of skin infection induced by methicillin-resistant S. aureus (MRSA) when administered at a dose of 5 µg and decreases the activity of the agr quorum sensing system in an in vivo reporter assay.Formal Name: (2E)-4-[(1R,5R,6R)-3-(1E)-1-hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid. CAS Number: 340774-69-8. Synonyms: (+)-Ambuic Acid. Molecular Formula: C19H26O6. Formula Weight: 350.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: soluble, Ethanol: soluble, Methanol: soluble. SMILES: OCC1=C(/C=C/CCCCC)C([C@@]2(C/C=C(C)/C(O)=O)[C@H](O2)[C@@H]1O)=O. InChi Code: InChI=1S/C19H26O6/c1-3-4-5-6-7-8-13-14(11-20)15(21)17-19(25-17,16(13)22)10-9-12(2)18(23)24/h7-9,15,17,20-21H,3-6,10-11H2,1-2H3,(H,23,24)/b8-7+,12-9+/t15-,17-,19+/m1/s1. InChi Key: UDSQZJMGPSRCEM-HDKVZZTHSA-N.
Keywords: (+)-Ambuic Acid, (2E)-4-[(1R,5R,6R)-3-(1E)-1-hepten-1-yl-5-hydroxy-4-(hydroxymethyl)-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-1-yl]-2-methyl-2-butenoic acid
Supplier: Cayman Chemical
Supplier-Nr: 27483

Properties

Application: Phytopathogenic, Antifungal, Quorum sensing inhibitory, Antibacterial agent
MW: 350.4 D
Formula: C19H26O6
Purity: >95%
Format: Solid

Database Information

CAS : 340774-69-8| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Ambuic Acid"
Write a review
or to review a product.
Viewed