Alvimopan
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl)... more
Product information "Alvimopan"
Description: Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut. Upon administration, this agent binds to mu-opioid receptors in the gut, thereby reversing opioid-related disturbances in gut motility. Alvimopan is approximately three to nine times more potent than naloxone. Target: Opioid Receptor. Smiles: C[C@H]1CN(C[C@H](Cc2ccccc2)C(=O)NCC(O)=O)CC[C@@]1(C)c1cccc(O)c1. References: Cassel JA, et al. Eur J Pharmacol. 2005 Sep 27,520(1-3):29-36.
| Supplier: | TargetMol |
| Supplier-Nr: | T1242 |
Properties
| Application: | µ-opioid receptor antagonist |
| MW: | 424.53 D |
| Formula: | C25H32N2O4 |
Database Information
| CAS : | 156053-89-3| Matching products |
| KEGG ID : | K04215 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H400 |
| P Phrases: | P264, P273, P280, P302+352, P305+351+338, P321, P332+313, P337+313, P362+364, P391, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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