alpha-Ketoglutaric Acid

alpha-Ketoglutaric Acid
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay33693-100 100 g -

6 - 10 business days*

43.00€
Cay33693-250 250 g -

6 - 10 business days*

85.00€
Cay33693-500 500 g -

6 - 10 business days*

156.00€
 
alpha-Ketoglutaric acid is an alpha-keto acid and a rate-determining metabolic intermediate in... more
Product information "alpha-Ketoglutaric Acid"
alpha-Ketoglutaric acid is an alpha-keto acid and a rate-determining metabolic intermediate in the citric acid cycle in its conjugate base form, alpha-ketoglutarate. It is formed via oxidative decarboxylation of isocitrate by isocitrate dehydrogenase (IDH), oxidative deamination of glutamate by glutamate dehydrogenase, or by pyridoxal phosphate-dependent transamination. alpha-Ketoglutaric acid is decarboxylated to succinyl-CoA by alpha-ketoglutarate dehydrogenase, a rate limiting step in the citric acid cycle. It is a precursor of glutamine and glutamate, energy sources for enterocytes and various immune cells, and an antioxidant with roles in immune homeostasis, aging, protein synthesis, and bone development.Formal Name: 2-oxo-pentanedioic acid. CAS Number: 328-50-7. Synonyms: alpha-KGA, NSC 17391, 2-Oxoglutaric Acid. Molecular Formula: C5H6O5. Formula Weight: 146.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O=C(C(CCC(O)=O)=O)O. InChi Code: InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10). InChi Key: KPGXRSRHYNQIFN-UHFFFAOYSA-N.
Keywords: 2-Oxoglutaric Acid, NSC 17391, alpha-KGA, 2-oxo-pentanedioic acid
Supplier: Cayman Chemical
Supplier-Nr: 33693

Properties

Application: Citric acid cycle intermediate
MW: 146.1 D
Formula: C5H6O5
Purity: >95%
Format: Solid

Database Information

CAS : 328-50-7| Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H318
P Phrases: P280, P305+351+338, P310
Caution
Our products are for laboratory research use only: Not for administration to humans!
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