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Description: Aleglitazar (R1439) (R1439) is a potent dual PPARalpha/gamma agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARgamma, respectively. Aleglitazar can be used for the research of type II diabetes. Target: PPAR. Smiles: C([C@@H](C(O)=O)OC)C1=C2C(=C(OCCC=3N=C(OC3C)C4=CC=CC=C4)C=C1)C=CS2. References: Bénardeau A, Verry P, Atzpodien EA, et al. Effects of the dual PPAR-alpha/gamma agonist aleglitazar on glycaemic control and organ protection in the Zucker diabetic fatty rat. Diabetes Obes Metab. 2013 Feb,15(2):164-74.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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