AKI603

Item number	Size	Delivery time	Price
TGM-T64338-1mg	1 mg	7 - 10 business days*	98.00€
TGM-T64338-5mg	5 mg	7 - 10 business days*	241.00€
TGM-T64338-1mL	1 ml	7 - 10 business days*	266.00€
TGM-T64338-10mg	10 mg	7 - 10 business days*	364.00€
TGM-T64338-25mg	25 mg	7 - 10 business days*	654.00€
TGM-T64338-50mg	50 mg	7 - 10 business days*	965.00€
TGM-T64338-100mg	100 mg	7 - 10 business days*	1,363.00€

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Description: AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3... more

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Product information "AKI603"

Description: AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2]. Target: Aurora Kinase. Smiles: CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Nc2ccc(cc2)[N+]([O-])=O)n1. References: Le-Xun Wang, et al. Aurora A Kinase Inhibitor AKI603 Induces Cellular Senescence in Chronic Myeloid Leukemia Cells Harboring T315I Mutation. Sci Rep. 2016 Nov 8,6:35533.

Keywords:	AKI-603, AKI 603
Supplier:	TargetMol
Supplier-Nr:	T64338

Properties

Application:	Aurora A kinase inhibitor
MW:	409.45 D
Formula:	C19H23N9O2

Database Information

CAS :	1432515-73-5\| Matching products
KEGG ID :	K11481 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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