AG-183

Description: (Z)-Tyrphostin A51, the Z configuration of Lanoconazole A51, is a potent protein tyrosine kinase (PTK) inhibitor that dose-dependently inhibits the volume-sensitive release of [3 H]taurine in primary astrocyte cultures. It significantly reduces cellular tyrosyl phosphorylation levels and inhibits both basal and EGF-induced human bone cell proliferation [1] [2]. Target: Others. Smiles: C(=C(/C(=C(C#N)C#N)N)\C#N)\C1=CC(O)=C(O)C(O)=C1