ADU-S100 ammonium salt

Description: ADU-S100 ammonium salt (ML RR-S2 CDA ammonium salt) is an activator of stimulator of interferon genes (STING). ADU-S100 ammonium salt leads to potent and systemic tumor regression and immunity. Target: STING. Smiles: NC1=C(C2=NC=N1)N=CN2[C@@H]3O[C@]([H])(CO4)[C@@]([H])(O[P@@](OC[C@@]5([C@]([H])([C@]([H])([C@@H](O5)N6C7=NC=NC(N)=C7N=C6)O[P@@]4(S)=O)O)[H])(S)=O)[C@H]3O.N.N. References: Corrales L, et al. Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity. Cell Rep. 2015 May 19,11(7):1018-30.