Adenosine

White to off white powder. Soluble in water (7mg/ml) or DMSO (75 mM). Insoluble in ethanol. Chemical. CAS: 58-61-7. Formula: C10H13N5O4. MW: 267.24. Adenosine is a purine nucleoside composed of adenine and ribose linked by a glycosidic linkage. Adenosine is a key endogenous neurotransmitter that regulates tissue function in an anti- and pro-inflammatory manner by activating four G-protein-coupled adenosine receptors: A1, A2A, A2B and A3, which serve diverse roles related to smooth muscle tone, central nervous system regulation and cardiac function. Cells of the immune system express these receptors and are responsive to the modulatory effects of adenosine in an inflammatory environment. Adenosine is a precursor for adenosine 5'-monophosphate, adenosine 5'-diphosphate, adenosine 5'-triphosphate and cyclic AMP.