Adenosine 3'-monophosphate (sodium salt hydrate)

Adenosine 3'-monophosphate is a nucleotide and metabolite formed via hydrolysis of 2',3'-cAMP by metal-dependent phosphodiesterases. It reduces proliferation of rat preglomerular vascular smooth muscles cells (PGVSMCs) and glomerular mesangial cells (GMCs) in a concentration-dependent manner, an effect that is abolished by the adenosine A2B receptor antagonist MRS1754. Adenosine 3'-monophosphate is also a metabolic intermediate in the biosynthesis of adenosine (Cay-21232).Formal Name: 3'-adenylic acid, sodium salt, hydrate. Synonyms: 3'-AMP. Molecular Formula: C10H14N5O7P . XNa [XH2O]. Formula Weight: 347.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 259 nm. SMILES: OC[C@@H]1[C@@H](OP(O)(O)=O)[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1.[Na].O. InChi Code: InChI=1S/C10H14N5O7P.Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20,,/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20),,1H2/t4-,6-,7-,10-,,/m1../s1. InChi Key: BAKJBUWNNRHUHN-IDIVVRGQSA-N.